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A recent European review of safety data for Zyban identified at least 8 cases of serotonin syndrome, a potentially life-threatening condition, where a possible interaction between bupropion and a. Bupropion is also the active ingredient in Wellbutrin, which is used to treat depression. You will begin taking Zyban while you're still smoking following a schedule: Days 1–3: One 150 milligram (mg) tablet once a day. 47. Muscle or joint pain. Anger and hostily, bursts of bad temper, agitation soon followed. ZYBAN ®(Bupropion Manufacturer’s Standard Smoking Cessation Aid Valeant Canada LP 2150 St. Medicines;. In addition to providing discount prescription drugs online, our Canada Pharmacy online offers a wide range of discounted over-the-counter (OTC) medications; this includes. The following side effects may get better over time as your body gets used to the medication Zyban 150mg Tablets 90 - Bupropion. Zyban is not sold over the counter, so you must see your doctor for a prescription. 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