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Enterotoxemia in cattle is caused by different types of this pathogen, including, according to some reports. It works by decreasing the amount of acid your stomach makes. It was also the first in its class to be approved for over-the-counter sale in 2003, under the name Prilosec OTC How is Prilosec OTC different from the other OTC treatments for heartburn? Learn More. Prilosec OTC starts working on Day 1*. Prilosec OTC, Omeprazole Delayed Release, Acid Reducer, Treats Frequent Heartburn for 24 Hour Relief, #1 Doctor Recommended Brand, 42 Tablets. It is available in both generic and brand versions, and without a prescription. It was also the first in its class to be approved for over-the-counter sale in 2003, under the name Prilosec OTC Walgreens Omeprazole Delayed Release Tablets 20 mg, Acid Reducer at Walgreens. 81. 383 reviews. 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